Drug Name: | Tranexamic Acid |
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Drug Class: | Antifibrinolytic agent |
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Mechanism of Action: | - Inhibits the activation of plasminogen to plasmin, which prevents the breakdown of fibrin clots
- Competitively inhibits the binding of plasminogen to fibrin, thereby reducing the formation of plasmin
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Use: | - Prevention and treatment of excessive bleeding due to surgery, trauma, or menstrual disorders
- Treatment of hereditary angioedema
- Off-label use in the management of epistaxis, hemoptysis, and hematuria
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Side Effects: | - Nausea, vomiting, and diarrhea
- Headache and dizziness
- Hypotension and tachycardia
- Seizures and visual disturbances
- Thromboembolic events (rare)
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Contraindications: | - Hypersensitivity to tranexamic acid
- Active thromboembolic disease
- History of seizures
- Renal impairment
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Specialty: | - Hematology
- Surgery
- Obstetrics and Gynecology
- Emergency Medicine
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